Volume 30, Issue 3, July-September 2023

Articles

• Testicular Toxicity following Subacute Exposure of Arsenic and Mancozeb alone and in Combination: Ameliorative Efficacy of Quercetin and Catechin

  Rasia Yousuf, Pawan Kumar Verma, Priyanka Sharma, Shilpa Sood, N. K. Pankaj, Sanjay Agarwal

  255-267

  Keywords:

  Arsenic, Catechin, Mancozeb, Quercetin, Testicular Damage

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  Abstract views: 8 times| Download: 0 times| https://doi.org/10.18311/ti/2023/v30i3/32276

• Protective Effect of L-Carnitine against Deltamethrin Induced Male Reproductive Toxicity in Adult Rats Exposed at their Prepubertal Stage

  Daveedu Thathapudi, Raja Jayarao Yendluri, Anilkumar Adimulapu, Mahesh Gunda, Manohar Vadela, S. B. Sainath, P. R. V. Manohar

  269-278

  Keywords:

  Deltamethrin, L Carnitine, Prepubertal Rats, Reproductive Toxicity

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  Abstract views: 4 times| Download: 0 times| https://doi.org/10.18311/ti/2023/v30i3/32261

• Cadmium-Induced Perturbation of Spleen Redox Status: Therapeutic Role of Pumpkin Seed Protein Isolate

  Siddhartha Singh, Oly Banerjee, Ishita Saha, Sudipta Kundu, Alak Kumar Syamal, Bithin Kumar Maji, Sandip Mukherjee

  279-288

  Keywords:

  Cadmium Toxicity, Cytokines, Oxidative Stress, PSPI, ROS, Spleen Histology

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  Abstract views: 8 times| Download: 0 times| https://doi.org/10.18311/ti/2023/v30i3/32544

• Toxicological Evaluation of Vaisvanara churna an Ayurvedic Formulation

  R. Ilavarasan, R. Arunadevi, Susan Thomas, Shrirang Balkrishna Jamadagani, Sudesh N. Gaidhani, M. Thenmozhi, N. Manikandan

  289-296

  Keywords:

  Acute Toxicity, Chronic Toxicity, Median Lethal Dose, NOAEL, Therapeutic Dose, Vaisvanara churna

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  Abstract views: 11 times| Download: 0 times| https://doi.org/10.18311/ti/2023/v30i3/33491

• Safety Evaluation of a Traditional Medicinal Plant, Flemingia vestita Benth and Hooker in Swiss Albino Mice: An Acute and Sub-acute Toxicity Study

  Aparmita Das, Arun Kumar Yadav, Bishnupada Roy

  297-308

  Keywords:

  Acute Toxicity, Flemingia vestita, Medicinal Plant, Sub-Acute Toxicity

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  Abstract views: 6 times| Download: 0 times| https://doi.org/10.18311/ti/2023/v30i3/32175

• Protective Effect of Pomegranate Juice Extract Against Antitubercular Drugs Induced Hepatic Fibrosis

  J. Ramesh, Anilkumar Banothu, Kala Kumar Bharani, P. Shivakumar, M. Jeevanalatha, Y. Ravikumar

  309-316

  Keywords:

  Antioxidants, Antitubercular Drugs, Hepatotoxicity, Pomegranate Juice, TGF Beta

  pharmacology and toxicology

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  Abstract views: 4 times| Download: 0 times| https://doi.org/10.18311/ti/2023/v30i3/30923

• Reverse Docking Approach Reveals the Negative Effect of Caffeine Toxicity on Glutamate GluR2 Receptor

  Hasan Ansari, Prekshi Garg, Radhika Rastogi, Rekha Sharma, Prachi Srivastava

  317-323

  Keywords:

  Caffeine, Glutamate GluR2, Neurological Disorders, Reverse Docking

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  Abstract views: 9 times| Download: 0 times| https://doi.org/10.18311/ti/2023/v30i3/33446

• Analysis of the Effects of Magnetic Field on the Haemogram Profile and Protein Content of Eri Silkworm, Philosamia ricini

  Shibani Kalita, Bidisha Rani Das, Sunayan Bardoloi, Smritimala Sarmah, Sanghamitra Saharia, Anjumani Ojah

  325-332

  Keywords:

  Electromagnetic Pollution, Haemogram, Magnetic Field, Silkworm

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  Abstract views: 10 times| Download: 0 times| https://doi.org/10.18311/ti/2023/v30i3/32165

• Impact of Amritikarana Procedure on Safety Aspect of Somanathi Tamra Bhasma

  Atul Dalvi, Mukesh Nariya, Swapnil Chaudhari, B. J. Patgiri

  333-341

  Keywords:

  Ayurveda, Amritikarana, Safety, Somanathi Tamra Bhasma, Tamra Bhasma, Toxicity

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  Abstract views: 5 times| Download: 0 times| https://doi.org/10.18311/ti/2023/v30i3/33602

• Phytochemical Screening and Evaluation of Antioxidant and Antiproliferative Potential of Morus alba (L.) Leaves Extracts Against Breast Cancer Cell Lines

  Richa Soni, Divya Gupta, Shamli Gupte, Arti Rathour, Sadhana Shrivastava, Sangeeta Shukla

  343-352

  Keywords:

  Antiproliferative Activity, Breast Cancer, Morus alba (L.), MTT (3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide)

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  Abstract views: 5 times| Download: 0 times| https://doi.org/10.18311/ti/2023/v30i3/33811

• Utilization of Mating Behavior as a Parameter to Understand Adaptive Response in Drosophila melanogaster using Ethyl Methanesulfonate and Methyl Methanesulfonate

  Baladare Udayakumar Divyashree, Kembalu Narayana Ravindra, Venkateshaiah Vasudev

  353-369

  Keywords:

  Adaptive Response, Challenging Dose, Combined Dose, Conditioning Dose, Courtship Elements, Drosophila melanogaster, EMS, MMS, Mating Behaviour

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  Abstract views: 8 times| Download: 0 times| https://doi.org/10.18311/ti/2023/v30i3/33469

• Development and Application of a Validated HPLC Method for the Determination of Alpelisib and its Process-Related Impurities in Pure Drug and Pharmaceutical Formulations

  Jammu Harish, Bodasingi Sai Kumar, Uppu Naga Babu, Gattupalli Subhakara Rao, Venkateswara Rao Anna

  371-382

  Keywords:

  Alpelisib, Formulation Analysis, HPLC Analysis, Method Development, Process Related Impurities

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  Abstract views: 13 times| Download: 0 times| https://doi.org/10.18311/ti/2023/v30i3/33573

• Estimation of Median Lethal Concentration (LC₅₀) of Pyrethroid and Carbamates Pesticides using the Nematode Caenorhabditis elegans to Predict Mammalian Acute Lethality (LD₅₀)

  Krishna Rana, Priyanka Gautam

  383-389

  Keywords:

  Carbamates, C. elegans, Median Lethal Concentration, Pyrethroids, Toxicity

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  Abstract views: 2 times| Download: 0 times| https://doi.org/10.18311/ti/2023/v30i3/31834

• Characterization and Preclinical Toxicity Assessment of Intranasal Administration of Standardized Extract of Centella asiatica (L.) Urban Leaves (INDCA-NS) in Laboratory Rats

  Prasad Thakurdesai, Savita Nimse, Pallavi Deshpande

  391-407

  Keywords:

  Acute Toxicity, Centella asiatica (L.) Urban Leaves, Intranasal, Subacute Toxicity, Total Triterpenoids

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  Abstract views: 8 times| Download: 0 times| https://doi.org/10.18311/ti/2023/v30i3/32171

• In vivo Acute Toxicity and Anti-inflammatory Activity of Ferula sulcata Desf. from Setif, Algeria

  Malika Rahmouni, Meriem Hamoudi, Randa Mlik, Hocine Laouer, Seddik Khennouf, Saliha Dahamna, Nour Elhouda Mekhadmi, Aicha Mouane

  409-418

  Keywords:

  Acute Toxicity, Anti-Inflammatory Activity, Essential oil, Ferula sulcata

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  Abstract views: 6 times| Download: 0 times| https://doi.org/10.18311/ti/2023/v30i3/33434