Ecotoxicological Studies of Cephalosporin Antibiotics on Daphnia Magna

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Authors

  • Aijaz Ahmad
     ,IN
  • Joydeep Dutta
     ,IN

DOI:

https://doi.org/10.18311/ti/2018/v25i3/22981

Keywords:

Cephalosporin, Non Target Organisms, Reproduction, Toxicity, Daphnia magna
Toxicology

Abstract

The present research was outlined to survey the intense and incessant poisonous quality of Cefixime and Cefotaxime antibiotics on Daphnia magna. The toxicity of Cefixime and Cefotaxime antibiotics was evaluated by 48h acute toxicity (US, EPA, 2002) and chronic toxicity (OECD guidelines 211 (OECD, 2012)). The data showed that EC50 of Cefixime was 78.78 mg/l and for Cefotaxime was 25.82 mg/l. Daphnia magna. showed more sensitivity to Cefotaxime, when compared with Cefixime antibiotic. Chronic toxicity showed that, Cefotaxime cause effects on reproduction but Cefixime had no adverse effect on Daphnia. The mortality rate enhanced and average number of neonates diminished as exposure to Cefotaxime antibiotic was increased. Daphnia. died (50%) at a concentration of 16.2 mg/l of Cefotaxime.

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Published

2019-10-22

How to Cite

Ahmad, A., & Dutta, J. (2019). Ecotoxicological Studies of Cephalosporin Antibiotics on <i>Daphnia Magna</i>. Toxicology International, 25(3), 169–178. https://doi.org/10.18311/ti/2018/v25i3/22981

Issue

Volume 25, Issue 3, July -September 2018

Section

Articles
Crossref
Scopus
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Europe PMC
Received 2018-12-12
Accepted 2019-02-21
Published 2019-10-22

 

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