Investigations into the Use of Xylopia aethiopica in the Treatment of Psoroptic Mange in Rabbits


  • University of Ibadan, Department of Veterinary Public Health and Preventive Medicine, Ibadan, Nigeria
  • Institute of Agricultural Research and Training, Federal College of Animal Health and Production technology, Ibadan, Nigeria
  • University of Ibadan, Department of Veterinary Physiology and Pharmacology, Ibadan, Nigeria


Objective: To evaluate the efficacy of Xylopia aethiopica (XA) in the treatment of mange in rabbits. Materials and methods: The efficacy of dried and grounded 30 g and 40 g of XA respectively mixed with 20 ml of palm oil was tested on different sets of mange infested rabbits and this was compared with sulphur, using 80 g of sulphur mixed with 20ml of palm oil. Results: XA was found to be more potent at 40 g relative to 80 g of sulphur, also the rabbits treated with 30 g and 40 g XA's weight gain during treatment was more significant (p< 0.05) than the control. Conclusion: Our study shows that Xylopia aethiopica exhibits remarkable anti-mange activity against psoroptic mange in rabbits. Further investigations into the isolation of the active constituent responsible for this action is recommended.


Xylopia aethiopica, Psoroptic Mange, Sulphur, Palm Oil.

Subject Discipline

Pharmacy and Pharmacology

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