Phytochemical Screening and Anti-Diabetic Efficacy of O. Sanctum Seed Extract on Streptozotocin Induced Diabetic Rats

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Authors

  • Kavitha K.
     Department of Foods and Nutrition, Vellalar College for Women, Erode, Tamilnadu ,IN
  • Ponne S.
     Department of Foods and Nutrition, Vellalar College for Women, Erode, Tamilnadu ,IN

DOI:

https://doi.org/10.21048/ijnd.2017.54.3.14976

Keywords:

Ocimum sanctum seed, anti-diabetic activity, phytochemicals
Foods and Nutrition

Abstract

The present study was designed to assess the in vitro and in vivo anti-diabetic efficacy of O. sanctum seed and its phytochemical screening. In vitro inhibitory effect on carbohydrate digestive enzymes like α-amylase and α-glucosidase and in vivo parameters such as fasting blood glucose and body weight changes were studied, a potent inhibitory effect was observed on activities of digestive enzymes and a marked decrease in the glucose level in the O. sanctum seed extract treated streptozotocin induced diabetic rats was noted. Further a marked reduction in body weight was also observed.

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Published

2017-07-04

How to Cite

K., K., & S., P. (2017). Phytochemical Screening and Anti-Diabetic Efficacy of <i>O. Sanctum</i> Seed Extract on Streptozotocin Induced Diabetic Rats. The Indian Journal of Nutrition and Dietetics, 54(3), 336–345. https://doi.org/10.21048/ijnd.2017.54.3.14976

Issue

Volume 54, Issue 3, July-September 2017

Section

Original Articles

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Europe PMC
Received 2017-04-24
Accepted 2017-05-16
Published 2017-07-04

 

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