A Study on the Clinical Profile of Non-Organophosphorus Poisoning in a Tertiary Care Hospital

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Authors

  • Anupam Dutta
     Department of General Medicine, Assam Medical College, Dibrugarh - 786002, Assam ,IN
  • Luish Borboruah
     Department of General Medicine, Assam Medical College, Dibrugarh - 786002, Assam ,IN
  • Juhi Bora
     Department of General Medicine, Assam Medical College, Dibrugarh - 786002, Assam ,IN
  • Prasanta Dihingia
     Department of General Medicine, Assam Medical College, Dibrugarh - 786002, Assam ,IN
  • Sreemanta Madhab Baruah
     Department of General Medicine, Assam Medical College, Dibrugarh - 786002, Assam ,IN

Keywords:

Acute Hepatitis, Acute Kidney Injury, Herbicide, Insecticide, Mortality, Non Organophosphorus Poisoning

Abstract

Poisoning is emerging as a very important global health issue particularly in agricultural countries like India. Although wide range of data is available on organophosphorus poisoning cases, studies and data are limited on non-organophosphorus compound poisoning like paraquat, rodenticide (zinc phosphide, yellow phosphorus, sodium monofluroacetate, fluroacetamide, arsenic, warfarins, and scilliroside etc.), pyrethroid, carbamate etc. The present study aims to study the clinical presentation and outcome of the non-organophosphorus poisoning cases. A cross sectional retrospective study was conducted at Assam Medical College and Hospital, Dibrugarh. In this study the data of the patients with nonorganophosphorus poisoning admitted to Assam Medical College from July, 2022 to July, 2023 were collected and analysed. A total of 104 patients were included in the study and most patients belonged to the age group of below 30 years. Out of all the cases highest number patients presented with Paraquat poisoning (48.1%), while distribution of other cases was as follows- Phenyl (12.5%), Pyrethroid (23.1%), Rodenticide (10.6%), Carbamate (1.9%) and Organochloride (3.6%). Vomiting was the most common presenting symptom. Hepatic and renal impairment was observed only in the paraquat poisoning cases and it was also associated with high mortality rate (88%). Acute Hepatitis and Acute kidney Injury was quite common among paraquat poisoning patients and mortality was mainly observed in paraquat, rodenticide and carbamate poisoning cases. Comprehensive care and awareness among general public is necessary for prevention and better management of poisoning cases. Development of proper rational management guidelines is also pivotal for reducing mortality in these cases.

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Published

2024-04-08

How to Cite

Dutta, A., Borboruah, L., Bora, J., Dihingia, P., & Baruah, S. M. (2024). A Study on the Clinical Profile of Non-Organophosphorus Poisoning in a Tertiary Care Hospital. Toxicology International. Retrieved from https://www.informaticsjournals.com/index.php/toxi/article/view/35652

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Online First

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Copyright (c) 2024 Anupam Dutta, Luish Borboruah, Juhi Bora, Prasanta Dihingia, Sreemanta Madhab Baruah

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Received 2023-11-24
Accepted 2024-02-01
Published 2024-04-08

 

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