Gas Chromotography-Mass Spectrometry Analysis of Ethanolic Fruit Extract of Momordica charantia var. Muricata

Abstract

The fruits of Momordica charantia (bitter gourd) have been used as folklore medicine for the management of ailments such as leprosy, menstrual problems, hypertension and most efficiently for diabetes. The present investigation was carried to identify active components in small round variety of immature fruit M. chrantia muricata was analysed. The fruits were procured directly from the garden at Bhuvanagiri, Tamil Nadu, were washed in tap water and cut into small pieces and were shade dried for 10 days. The dried fruits were ground into fine powder. The sample was extract with ethanol and analyzed through Gas Chromatography-Mass spectrometry for identification of different compounds. Analysis revealed presence of 25 phyto components. The major compound present in the ethanolic fruit extract was identified as β-Sitosterol with RT 37.26 and 12.16% relative peak area. This compound has antihyperlipoproteinaemic, antibacterial and antimicotic activity, and helps tumor inhibition in vivo.