Investigation of Neuropharmacological Activities of Ethanolic Extract of Dodonaea viscosa Seeds


Affiliations

  • Bapuji Pharmacy College, Davangere, 577002, India
  • Kuvempu University, Shimoga, Karnataka, 577451, India
  • Manipal University, Department of Pharmacognosy, Manipal College of Pharmaceutical Sciences, Mahe, Manipal, 576104, India

Abstract

Objective: To study the neuropharmacological activities of the ethanolic extract of Dodonaea viscosa seeds. Materials and methods: Neuropharmacological activities includes behavioural assessment, pentobarbitone-induced sleeping time, motor coordination activity and locomotor activity of the Dodonaea viscosa seeds ethanolic extract was evaluated at the dose of 30 mg/kg and 20 mg/kg (p.o.) respectively. Results: Ethanolic extract of Dodonaea viscosa seeds potentiated phenobarbitone - induced sleeping time, reduced locomotion and the same extract did not induce motor in coordination at dose levels of 30 mg/kg and 20 mg/kg (p.o.). Conclusion: The results of present study have revealed that the ethanolic extract of Dodonaea vsiscosa showed excellent neuropharmacological activities and there is a scope for further envisage.

Keywords

Dodonaea viscosa Seeds, Ethanolic Extract, Hypnosis, Rotarod, Actophotometer.

Subject Discipline

Pharmacy and Pharmacology

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