TY - JOUR AU - Al-Rosyid, Latifa Mirzatika AU - Santoso, Irwan Bagyo AU - Titah, Harmin Sulistiyaning AU - Mangkoedihardjo, Sarwoko AU - Trihadiningrum, Yulinah AU - Hidayati, Dewi PY - 2022/12/12 Y2 - 2024/03/28 TI - Correlation between BOD/COD Ratio and Octanol/Water Partition Coefficient for Mixture Organic Compounds JF - Toxicology International JA - TI VL - 29 IS - 3 SE - Research Articles DO - 10.18311/ti/2022/v29i3/29141 UR - https://www.informaticsjournals.com/index.php/toxi/article/view/29141 SP - 329-337 AB - <p><span lang="EN-US">Correlation between the BOD/COD ratio and Partition coefficient of octanol/ water (Pow) on a single organic substance shows that the Pow value is directly proportional to the toxicity level and inversely proportional to BOD/COD ratio. This research examined the correlation to a mixture of organic substances. The objective is to obtain a varied range of substances, as well as determining the quality of wastewater discharging to fresh waters. Need for analysis of organic substances used as antiseptics during the Covid-19 pandemic. In addition, organic substances from the organophosphate pesticide class, diazinon, were used. BOD5, COD, Pow, and LC50-96h toxicity tests using Daphnia magna were used. Six types of the mixture of organic substances included diazinon-formaldehyde-isopropyl alcohol, ethanol-oxalic acid-formaldehyde, isopropyl alcohol-glycerol-lactose, acetic acid-isopropyl alcohol-formaldehyde, sucrose-glycerol-acetic acid, and oxalic acid-formaldehyde-diazinon, with 3 different concentrations of 10, 100, and 1000 mg/L, three repetitions. The lowest BOD/COD ratio (&lt;0.2) and the highest Pow value (&gt;4) are found in diazinon-formaldehyde-IPA. Its toxicity in D. magna also showed the lowest LC-50 (11.82 mg/L). Whereas, sucrose-glycerol-acetic acid had the highest BOD/COD ratio (&gt;0.7) and lowest Pow (&lt;0.7) with the highest LC- 50 (567.88 mg/L). Other organic substances mixtures have characteristics in the range of these mixtures. Pow variability and the BOD/COD ratio have a negative correlation. A mixture of organic matter is more biodegradable making it has a higher tendency to dissolve in water.</span></p> ER -