TY - JOUR AU - Ahmad, Aijaz AU - Dutta, Joydeep PY - 2019/10/22 Y2 - 2024/03/28 TI - Ecotoxicological Studies of Cephalosporin Antibiotics on Daphnia Magna JF - Toxicology International JA - TI VL - 25 IS - 3 SE - Articles DO - 10.18311/ti/2018/v25i3/22981 UR - https://www.informaticsjournals.com/index.php/toxi/article/view/22981 SP - 169-178 AB - The present research was outlined to survey the intense and incessant poisonous quality of Cefixime and Cefotaxime antibiotics on <em>Daphnia magna.</em> The toxicity of Cefixime and Cefotaxime antibiotics was evaluated by 48h acute toxicity (US, EPA, 2002) and chronic toxicity (OECD guidelines 211 (OECD, 2012)). The data showed that EC<sub>50</sub> of Cefixime was 78.78 mg/l and for Cefotaxime was 25.82 mg/l. <em>Daphnia magna.</em> showed more sensitivity to Cefotaxime, when compared with Cefixime antibiotic. Chronic toxicity showed that, Cefotaxime cause effects on reproduction but Cefixime had no adverse effect on <em>Daphnia.</em> The mortality rate enhanced and average number of neonates diminished as exposure to Cefotaxime antibiotic was increased. <em>Daphnia.</em> died (50%) at a concentration of 16.2 mg/l of Cefotaxime. ER -