TY - JOUR AU - Saxena, Ronika AU - Garg, Poonam AU - Jain, D. K. PY - 2018/05/21 Y2 - 2024/03/29 TI - In Vitro Anti-oxidant Effect of Vitamin E on Oxidative Stress Induced due to Pesticides in Rat Erythrocytes JF - Toxicology International JA - TI VL - 18 IS - 1 SE - Original Research DO - UR - https://www.informaticsjournals.com/index.php/toxi/article/view/21317 SP - 73-76 AB - An attempt was made to study the antioxidant property of vitamin E in endosulfan and chlorpyrifos toxicity. Erythrocytes were collected from healthy rats and exposed to 1 ppm endosulfan and chlorpyrifos pesticides individually and also along with vitamin E treatment. Results showed that endosulfan was more toxic in comparison of chlorpyrifos. Activities of superoxide dismutase and catalase were significantly decreased, while lipid peroxidation and glutathione-S-transfarase were increased in comparison to the control values. The results of the present study suggest that vitamin E acts as an effective antioxidant for endosulfan and chlorpyrifos pesticide toxicity, in reducing oxidative stress burden. ER -