@article{Swapna_Reddy_Reddy_2018, title={Cadmium-induced Oxidative Stress and Evaluation of <i>Embilica officinalis</i> and Stressroak in Broilers}, volume={17}, url={https://www.informaticsjournals.com/index.php/toxi/article/view/21175}, abstractNote={Cadmium (Cd) toxicity was studied in broilers, and efficacy of &lt;em&gt;Emblica officinalis&lt;/em&gt; (500 ppm in feed), vitamin E (300 ppm in feed), and stressroak (1 g/kg feed) were evaluated for prophylactic and therapeutic management of Cd toxicity. One-day-old male broiler chicks were randomly divided into eight groups consisting of 10 chicks in each. Groups 1 and 2 were maintained as plain control and Cd (100 ppm in feed) toxic control (for six weeks). Groups 3, 4, and 5 were maintained on a combination of Cd (100 ppm in feed) and &lt;em&gt;Emblica officinalis&lt;/em&gt;, vitamin E, and stressroak for six weeks. Groups 6, 7, and 8 were maintained with Cd for the first four weeks and on &lt;em&gt;Emblica officinalis&lt;/em&gt;, vitamin E, and stressroak during the subsequent two weeks without Cd. Body weights, feed consumed, Feed conversion ratio (FCR), and glulathione (GSH) were significantly (P&amp;lt;0.05) decreased, whereas the activities of antioxidant enzymes (catalase and Superoxide dismutase (SOD)) and concentration of Thiobarbituric acid reacting substances (TBARS) were significantly (P&amp;lt;0.05) increased in toxic control group. After treatment with &lt;em&gt;Emblica officinalis&lt;/em&gt;, vitamin E, and stressroak in groups 6, 7, and 8 during last two weeks and discontinuation of Cd, the parameters revealed improvement. From this study, it is concluded that Cd induces toxicity by oxidative stress, and supplementing &lt;em&gt;Emblica officinalis&lt;/em&gt;, vitamin E, and stressroak in feed is useful in preventing and treating the toxicity.}, number={2}, journal={Toxicology International}, author={Swapna, G. and Reddy, A. Gopala and Reddy, A. Rajasekhar}, year={2018}, month={May}, pages={49–51} }