Safety/Toxicity studies of Ayurvedic formulation-Navratna rasa

Authors

  • Central Council for Research in Ayurveda and Siddha , Janakpuri, New Delhi-110058
  • CCRAS Pharmacological Research Unit, (G.A.U.), Jamnagar
  • Central Council for Research in Ayurveda and Siddha , Janakpuri, New Delhi-110058
  • Central Council for Research in Ayurveda and Siddha , Janakpuri, New Delhi-110058
  • CCRAS Pharmacological Research Unit, (G.A.U.), Jamnagar
  • CCRAS Pharmacological Research Unit, (G.A.U.), Jamnagar

Keywords:

Ayurvedic drug, toxicity, rats

Abstract

Navratna rasa, an ayurvedic proprietary medicine based on classical formulation has been in use since long for general debility, rickets and calcium deficiency in Ayurvedic practices. The drug was screened for its safety/toxicity studies in acute and chronic models. No mortality and behavioral changes were observed during the course of acute toxicity study. The chronic toxicity study reveals that, the test drug has no serious toxicity potential to most of the important organs in therapeutics doses.

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References

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Saper, R.B., Kales, S.N., Paquin, J., Barns, M.J., Eisenberg, D.M., Davis, R.B. and Phillips, R.S. (2004). Heavy metal content of Ayurvedic herbal medicine products. JAMA, 292: 2868-2873.

Paget, G.E. and Branes, G.M.(1964). Evaluation of Drug Activities: Pharmacometrics eds, Laurance and Bacharach, Vol.1. Academic Press, New York.

WHO (2004). Guidelines for Quality standardized herbal formulations.

Published

2018-04-05

How to Cite

G. S., L., B., R., S., V. R., S. N., G., B. K., A., & V. J., S. (2018). Safety/Toxicity studies of Ayurvedic formulation-Navratna rasa. Toxicology International, 16(1), 37–42. Retrieved from https://www.informaticsjournals.com/index.php/toxi/article/view/20842

Issue

Section

Original Research