Antidiabetic Activity of Barleria prionitis Linn.

Abstract

Objective: To study antidiabetic effect of various parts of B. prionitis. Materials and methods: Antidiabetic activity of B. prionitis was evaluated using alloxan induced hyperglycemic rats. The potency of alcoholic and aqueous extracts of leaf, stem and root was compared with that of chlorpropamide at a dose of 200 and 100mg/kg respectively. The blood glucose level was measured colorimetrically. Results: Alcoholic & aqueous extracts of leaf and root caused significant fall in blood glucose level in diabetic rats. Conclusion: B. prionitis is almost equipotent to chlorpropamide in its ability to reduce the sugar levels and can be recommended for further studies.