A Review Article on the Role of Ingredients of Kshara Vasti (Medicated Enema) on Gut Microbiota of Rheumatoid Arthritis Patients

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  • Department of Panchakarma, All India Institute of Ayurveda, New Delhi – 110076 ,IN
  • Department of Panchakarma, GS Ayurveda Medical College, Pilkhuwa – 245304, Uttar Pradesh ,IN
  • Savitribhai Phule Pune University, Pune – 411007, Maharashtra ,IN
  • Department of Panchakarma, All India Institute of Ayurveda, New Delhi – 110076 ,IN
  • Department of Panchakarma, All India Institute of Ayurveda, New Delhi – 110076 ,IN




Amavata, Ayurveda, Gut Microbiota, Kshara Vasti, Niruha Vasti, Rheumatoid Arthritis


Kshara Vasti (medicated enema) is an important treatment in the management of Amavata which is correlated with Rheumatoid Arthritis (RA). The ingredients of Kshara Vasti have the property to act against Ama which is a root cause of the development of the disease. The main aim of this review is to study the role of ingredients of Kshara Vasti on the gut microbiota of RA patients. Jaggery, tamarind and rock salt have been proven to have a positive effect on the gut microbiome by enhancing the abundance of health-promoting species. Cow’s Urine (CU)/Cow Urine Distillate (CUD) enhances the bioavailability and efficacy of a drug with which it is co-administered. Anethum sowa has a significant impact on caecal microbiota. The production of Short-Chain Fatty Acids (SCFAs ) by Gut Microbiota (GM) may be a probable mode of action for the suppression of inflammatory conditions like RA. Each constituent in Kshara Vasti has a positive impact on modulating gut microbiota.


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Aswathy, Y. S., Prathibha, C. K., Raman, S., Dharmarajan, P., & Anandaraman, P. V. (2024). A Review Article on the Role of Ingredients of <i>Kshara Vasti</i> (Medicated Enema) on Gut Microbiota of Rheumatoid Arthritis Patients. Journal of Natural Remedies, 24(4), 749–756. https://doi.org/10.18311/jnr/2024/35468



Short Review


Received 2023-10-27
Accepted 2024-02-23
Published 2024-04-01



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