A Review on Probiotic and Microbiota Modulation: A Promising Nutraceutical in the Management of Neurodegenerative and Psychiatric Conditions

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  • Noida Institute of Engineering and Technology (Pharmacy Institute), 19 Knowledge Park II, Greater Noida - 201306, Uttar Pradesh ,IN
  • Noida Institute of Engineering and Technology (Pharmacy Institute), 19 Knowledge Park II, Greater Noida - 201306, Uttar Pradesh ,IN
  • Noida Institute of Engineering and Technology (Pharmacy Institute), 19 Knowledge Park II, Greater Noida - 201306, Uttar Pradesh ,IN
  • Noida Institute of Engineering and Technology (Pharmacy Institute), 19 Knowledge Park II, Greater Noida - 201306, Uttar Pradesh ,IN




Microbiota, Neurodegenerative Disease, Pharmacology, Probiotics, Psychiatric Disease


Microbes as probiotics were found to provide the host with health benefits when given in proper doses. Researches are going on to analyze the positive relation of probiotics on digestive health including the changes in the microbial populations in the gut. The immune, nervous, and endocrine system are some of the locations outside of the gut that is affected by probiotics. The study focussed on the potential impact of the “microbiota-gut-brain axis” on CNS-related functions. The role of probiotics is highlighted in our study for the control of a number of CNS illnesses, including Alzheimer’s disease, anxiety, obsessive-compulsive disorder, etc. This review also provides an overview of some clinically proven commercial probiotics and clinical studies reporting the impact of probiotics augmentation in cognition and symptoms in individuals with severe neurological and psychiatric illnesses.


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Author Biographies

Anmol Kanda, Noida Institute of Engineering and Technology (Pharmacy Institute), 19 Knowledge Park II, Greater Noida - 201306, Uttar Pradesh

as Author

Saumya Das, Noida Institute of Engineering and Technology (Pharmacy Institute), 19 Knowledge Park II, Greater Noida - 201306, Uttar Pradesh

as Author

Vishnu Prabhakar, Noida Institute of Engineering and Technology (Pharmacy Institute), 19 Knowledge Park II, Greater Noida - 201306, Uttar Pradesh

as author




How to Cite

Kanda, A., Mazumder, A., Das, S., & Prabhakar, V. (2023). A Review on Probiotic and Microbiota Modulation: A Promising Nutraceutical in the Management of Neurodegenerative and Psychiatric Conditions. Journal of Natural Remedies, 23(4), 1209–1222. https://doi.org/10.18311/jnr/2023/33944



Review Articles
Received 2023-06-01
Accepted 2023-07-18
Published 2023-11-08



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