Anti-Inflammatory Activity of Ziziphus jujuba Lam Leaves Extract in Rats

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  • ,IN
  • ,IN
  • ,IN
  • ,IN

DOI:

https://doi.org/10.18311/jnr/2004/185

Keywords:

Anti-Inflammatory, Carrageenan, Inflammation, Ziziphus jujuba.
Therapeutic Drug Monitoring

Abstract

Objective: To evaluate the anti-inflammatory activity of the alcoholic extract of Ziziphus jujuba Lam leaves in albino rats. Materials and methods: Ziziphus jujuba leaves were extracted with 90 % ethanol and the extract was screened for anti-inflammatory activity at the doses of 200, 400 and 600 mg/kg using acute carrageenan induced paw oedema in albino rats. Diclofenac sodium (100 mg/kg, p.o.) was used as standard reference drug. Results: The % inhibition of paw edema at 3 h after carrageenan administration produced by Ziziphus jujuba leaves extract at the dose of 200, 400 and 600 mg/kg was 44.5%, 62.2% and 81.8% respectively when compared to control. The paw oedema attenuating effect of Ziziphus jujuba leaves extract at the dose of 600 mg/kg was comparable with that produced by diclofenac sodium (88.6%). Conclusion: The present study indicates that Ziziphus jujuba leaves extract possess significant anti-inflammatory activity against carrageenan-induced rat paw edema.

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Published

2004-06-01

How to Cite

Kumar, S., Ganachari, M. S., Banappa, ., & Nagoor, V. S. (2004). Anti-Inflammatory Activity of <I>Ziziphus jujuba</I> Lam Leaves Extract in Rats. Journal of Natural Remedies, 4(2), 183–185. https://doi.org/10.18311/jnr/2004/185

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Short Communication