Chemical and Biological Studies of Euphorbia aphylla


  • Assiut University, Department of Pharmacognosy, Faculty of Pharmacy, Assiut, 71526, Egypt


From the aerial part of Euphorbia aphylla, nine compounds were isolated (1-9) and identified by different spectral techniques as well as comparison with authentic samples. The isolated compounds included two triterpenes (β-amyrone (1) and euphol(2)), two sterols (β-sitosterol (3) and β-sitosterolglucoside (4)) and five phenolic compounds (gallic acid (5), quercetin (6), quercetin-3-O-(2'',3''-digalloyl)-α-l-rhamnoside (7), 3,4,3'-O-trimethyl ellagic acid 4'-O-β-d-glucopyranoside (8) and (3,4,3'-tri-O-methyl ellagicacid4'-rutinoside)(9)).

The anti-inflammatory, anti pyretic,and antioxidant and antimicrobial activities were carried out on different plant fractions.


Euphorbia aphylla, Ellagic Acid Derivatives, Triterpenes, Flavonoids, Anti-Inflammatory, Antioxidant, Antimicrobial Activity.

Subject Discipline

Pharmacy and Pharmacology

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