TY - JOUR AU - Mohan, Sini AU - Nair, Gokul G. AU - Prabhakar, Reshma AU - N. A., Malini AU - George K, Roy PY - 2022/11/25 Y2 - 2024/03/29 TI - Effects of Sub-lethal Concentrations of Plasticizer - Diethyl Phthalate on a few Reproductive Indices of Female Freshwater Murrel, Channa striatus (Bloch) JF - Journal of Endocrinology and Reproduction JA - JER VL - 26 IS - 3 SE - Original Research DO - 10.18311/jer/2022/29363 UR - https://www.informaticsjournals.com/index.php/jer/article/view/29363 SP - 171-178 AB - <p>Diethyl phthalate (DEP) is used as a plasticizer and arrives at the aquatic environment from different industries and can cause deleterious effects to fish. Great concern regarding the effects of these compounds in nature has evolved as a consequence to their endocrine-disrupting properties. Most of the studies on the endocrine-disrupting effects of chemicals in nature are based on their effects on the reproduction of fish and on changes in their genital structures. In the present study, the effect of exposure of female <em>Channa striatus</em> to DEP has been investigated. The treatment caused reduction in gonadosomatic index, ova diameter and fecundity. This may be due to the endocrine disrupting activity of this chemical. Histopathological examination of the ovary of DEP-exposed fish showed dose-dependent regressive changes as a result of estrogenic endocrine disruption. The present study strongly suggests that DEP induces endocrine disruption adversely affecting the reproductive potential of female <em>Channa striatus</em>.</p> ER -