Osteosarcoma of Jaw - Case Report and Review of Literature


Affiliations

  • Punjab Institute of Medical Sciences, Department of Oral & Maxillofacial Surgery, Jalandhar, Punjab, India
  • Punjab Institute of Medical Sciences, Department of Plastic Surgery, Jalandhar, Punjab, India

Abstract

Osteosarcoma is a bone tumor and can occur in any bone, usually in the extremities of long bones, near the metaphyseal growth plates. Osteosarcoma of the jaw bones represents a distinct group of lesions from the conventional type commonly occurring in long bones. The emphasis should be laid on the aggressiveness of this lesion which warrants an early identification and diagnosis of the lesion followed by prompt treatment. True synchronous multicentric osteosarcomas of the jaws are extremely rare but, like other osteosarcomas of the jaws, have a favourable outcome, and palliative resection of such lesions, though challenging, can therefore lead to an enormously improved quality of life and self-image, and may even offer the opportunity for cure. We present a case of osteosarcoma of mandible in a young male treated by radical excision and reconstruction using free fibula bone flap.

Keywords

Bony Swelling, Osteosarcoma, Jaws, Radical Surgery, Reconstruction.

Subject Discipline

Dentistry

Full Text:

References

Mardinger O, Givol N, Talmi YP, Taicher S, Saba K, Tel Aviv, et al. Osteosarcoma of Jaws. Oral Surg Oral Med Oral Pathol Oral Radio Endod 2001 Apr;91(4):445-51.

Khorate MM, Goll S, Singh MP, Ahmed J. Osteosarcoma of Mandible: A Case Report and Review of Literature. J Cancer Sci Ther 2010;2:122-25.

Soares RC, Soares AF, Soreza LB, Dos Santos ALV, Pinto LP. Osteosarcoma of mandible initially resembling a lesion of dental periapex: A Case Report. Rev Bras Otorrhinology 2005;71: 242-45.

Shetty DC, Ahuja P, Aditya B, Kaur R. Histopathological variants of Jaw Osteosarcoma. International Journal of Pathology 2009;7(2):98-101.

Dehner LP. The enigmatic inflammatory pseudotumors: The current state of our understanding or misunderstanding. Journal of Pathology 2000;192:277-279.

Guard MS, John A, Unarji HR. Osteosarcoma of mandible. A Case Report. Journal of Indian Academy of Oral Medicine and Radiology 2005;17(03):110-113.

Frei C, Bornstein MM, Slauffer E, Fizuka T, Buser D. Osteosarcoma of Maxilla and Maxillary Sinus. A Case Report. Quintessance Int 2004;35:228-233.

Cabrel LA, Werkman C, Brando AA, Almeida JD. Imprint Cytology of Osteosarcoma of jaw. A Case Report. J Med Case Reports 2009 Dec 11;3:9327.

Yoon JH, Yook JI, Kim HJ, HO Chai, Kim J. Periosteal osteosarcoma of the mandible. J Oral Maxillofacial Surg 2005;63:699-703.

Clark JL, Unni KK, Dahlin DC, Devine KD. Osteosarcoma of the jaw. Cancer 1983;51:2311-2316.

Panicek DM, Galsonis C, Rosenthan DI, Seeger LL, Huos AG, Moore SG et al. CT and MR Imaging in the local staging of primary malignant musculoskeletal neoplasms, Report of the Radiology Diagnostic Oncology Group. Radiology 1997;202:237-246.

Bennet JH, Thomas G. Evans AW, Speight PM. Osteosarcoma of the jaws: A 30 year Retrospective Review. Oral Surg Oral Med Oral Pathol Oral Radiol Endod 2000 Sept;90(3):323-332.

Unni KK, Dahlin DC. Grading of Bone tumors. Seminar Diag Patho 1984;1:165-172.

Ozaki T, Scharfer KL, Wai D, Buregur H, Flerge S, Undover N et al. Genetic imbalance revealed by comparative genomic hybridization in osteosarcomas. Int J Cancer 2002;102-355-65.

Serra M, Naurici D, Skollandir K, BarbanticBrodano G, Nanara MC, Benover S et al. Relationship between P. Glyocoprotein expressions and p53 status in high grade osteosarcoma. Int J Oncol 1999;14:301-307.


Refbacks

  • There are currently no refbacks.