Antimicrobial Activity of White and Pink Nelumbo Nucifera Gaertn Flowers


Affiliations

  • P S G College of Arts and Science, Department of Biochemistry, Coimbatore, Tamil Nadu, 641 014, India

Abstract

Nelumbo nucifera Gaertn (Family: Nelumbonaceae), medicinally versatile and used as an important raw material of age-old traditional medical practices like Ayurveda and folk medicine. Bioassays for antimicrobial activities were carried out using hydroethanolic extract of both white and pink flowers of Nelumbo nucifera Gaertn plant. Both the flower extracts were tested against five important bacterial strains and two fungal strains. Further, Minimum Inhibitory Concentration (MIC) was evaluated against Escherichia coli (gram negative) and Staphylococcus aureus (gram positive) organisms. Both the flower extracts showed considerable activity against all tested bacteria and fungi strains. The white and pink flower extracts more or less showed similar antimicrobial activities. MIC for white flower extract against Escherichia coli and Staphylococcus aureus was found to be 430μg and 450μg respectively and pink flower showed 480μg and 490μg respectively. The antibacterial and antifungal activities of both flower extracts were comparable to those of selected chemical antibiotics suggesting their potential as alternatives to orthodox antibiotics in the treatment of infectious caused by these microorganisms.

Keywords

Nelumbo nucifera Gaertn, Antibacterial Activity, Minimum Inhibitory Concentration (MIC), Antifungal Activity, Agar Disc Diffusion.

Subject Discipline

Pharmacy and Pharmacology

Full Text:

References

Parekh J, Chanda S, In vitro antibacterial activity of the crude methanol extract of Woodfordia fruticosa Kurz. Flower (Lythraceae), Brazilian Journal Microbiology, 38, 2007, 204-207.

Kumaraswamy MV, Kavitha HU, Satish S, Antibacterial evaluation and phytochemical analysis of Betula utilis against some human pathogenic bacteria, World journal of Agricultural Sciences, 4(5), 2008, 661-664.

Benkeblia N, Antimicrobial activity of essential oil extracts of various onions (Allium cepa) and garlic (Allium sativum), Turk J. Biol., 37, 2004, 263-268.

Liu CP, Tsai WJ, Lin YL, Chen CF, Kuo YC, The extracts from Nelumbo nucifera suppress cell cycle progression, cytokine genes expression, and cell proliferation in human peripheral blood mononuclear cells, Life Science, 75, 2004, 699– 716.

Kashiwada Y, Asoshima A, Ikeshiro Y, AntiHIV benzylisoquinoline alkaloids from leaves of Nelumbo nucifera and structure activity correlations with related alkaloids, Bioorg Med Chem., 13, 2005, 443-448.

Saengkhae C, Arunnopparat W, Sungkhajorn P, Antioxidant activity of Nelumbo nucifera Gaertn on oxidative stress-induced Erythrocyte hemolysis in hypertensive and normotensive rats, Journal of physiological sciences, 20, 2008, 7078.

Sridhar KR, Rajeev B, Lotus-A potential nutraceutical source. Journal of Agricultural Technology, 3, 2007, 143-155.

Bensky D, Clavey S, Stoger E, Materia Medica, Eastland Press Inc, USA. 2004, 3: 193–194.

Tongtorsak P, Chaichit N, Panyajirawut J, Acute and chronic hypotensive effects of crude leaf extract of Nelumbo nucifera Gaertn, TJPS, 17, 2004, 68-69.

Mukherjee PK, Saha K, Saha BP, Effect of Nelumbo nucifera rhizome extract on blood sugar level in rats, Journal of Ethnopharmacology, 58, 1997, 207-213.

Parekh j, Nair R, Chanda S, Preliminary screening of some folklore medicinal plants from western India for potential antimicrobial activity, Indian Journal of Pharmacology, 37, 2005, 408409.

Eucast definitive Document E. Def. 3.1. European Committee for antimicrobial susceptibility testing: “Determination of minimum inhibitory concentrations (MICs) of antibacterial agents by agar dilutionâ€, Clin. Microbial & Infec., 6, 2000, 509-515.

Deepa N, Rajendran NN, Lata T, Jagannathan NS, Antibacterial and antifungal activities of ethyl acetate extract and the isolated fractions of Acanthospermum hispidum DC, Journal of Natural Remedies, 2, 2004, 190-194.

Bose A, Mondal S, Gupta JK, Ghosh T, A study on antimicrobial activity of Cleome rutidosperma DC, Journal of Natural remedies, 7, 2007, 132134.

Rogger Y, Stanier L, Mark L, Assessment of antimicrobial and antifungal activity of common medicinal plants, International Journal of Pharmacology, 3(6), 2000, 499-504.

Ushimaru T, Silva G, Antibacterial activity of common plants against different bacterial strains, Food Chem., 29, 2007, 275-283.

Ravindra T, Russel H, Willams T, Antifungal activity of methanolic extract of Capparis pepiaria against the tested fungal strains. J. Ethanopharmacol, 8, 2007, 109-114.


Refbacks

  • There are currently no refbacks.