Computational Studies of Sirtuins in the Treatment of Type II Diabetes mellitus


Affiliations

  • GITAM University, Department of Bioinformatics, Visakhapatnam, A. P., 530002, India

Abstract

Ageing in humans refers to a biological process of life engaged with physical, psychological, and social changes. Different species of animals age at radically different paces and occurrences of diseases. D rug designing approaches related to an aging factor, Type 2 Diabetes mellitus has been reported in the present study. Resveratrol and human Sirtuins (1 to 6) are docked against Type 2 Diabetes mellitus HNF - 1a motif with PDB ID: 2GYP using Hex 5.1. Resveratrol and Sirtuin 6 shown good results and can use as anti - aging drugs against Type 2 Diabetes mellitus.

Keywords

Drug Designing, Ageing, Type 2 Diabetes Mellitus, Docking.

Subject Discipline

Pharmacy and Pharmacology

Full Text:

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