Phytochemical Studies, Anti-Oxidant and Anti- Inflammatory Properties of Four Medicinal Plants

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Authors

  • Ayushi Sharma
     Department of Biotechnology, GLA University, Mathura - 281406, Uttar Pradesh ,IN
  • Anjana Goel
     Department of Biotechnology, GLA University, Mathura - 281406, Uttar Pradesh ,IN

DOI:

https://doi.org/10.18311/jeoh/2023/34716

Keywords:

Anti-Inflammatory Agents, Anti-Oxidant Activities, Nyctanthes arbor-tristis, Phytochemical Analysis, Rheumatoid Arthritis

Abstract

Rheumatoid arthritis, a chronic autoimmune disorder, is characterized by polyarthralgia and joint dysfunction resulting from autoimmune responses that target self-neoepitopes. These attacks lead to the activation of macrophages and other defense cells. By identifying these self-epitopes as biomarkers in RA, researchers have gained valuable insights into the disease’s pathogenesis. Over the years, research has focused on investigating the potential of medicinal plants as antiinflammatory agents. In this study, a hydroethanolic extract of Saraca asoca, Ficus benghalensis, Chenopodium album, and Nyctanthes arbor-tristis leaves was prepared by Soxhlet apparatus. Various concentrations of extracts were utilized to assess phytochemical analysis, GC-MS, in-vitro anti-oxidant, and anti-inflammatory activities. The highest scavenging potential was exhibited by Chenopodium album, as assessed by the DPPH assay (90.32 ± 3.2 %) and H2O2 (86.00 ± 1.94 %). Similarly, the Nyctanthes arbor-tristis showed (92.23 ± 0.83 %) inhibition in membrane stabilization assay, and (91.49 ± 1.03 %) in protein denaturation inhibition capacity. GCMS analysis showed various phytoconstituents in extracts. In order to confirm its therapeutic potential for treating RA, Nyctanthes arbor-tristis may be a better drug candidate that needs to be further researched for mechanistic studies.

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Published

2023-12-15

How to Cite

Sharma, A., & Goel, A. (2023). Phytochemical Studies, Anti-Oxidant and Anti- Inflammatory Properties of Four Medicinal Plants. Journal of Ecophysiology and Occupational Health, 23(4), 305–316. https://doi.org/10.18311/jeoh/2023/34716

Issue

Volume 23, Issue 4, December 2023

Section

Research Article

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Copyright (c) 2023 Ayushi Sharma, Anjana Goel

Creative Commons License

This work is licensed under a Creative Commons Attribution 4.0 International License.

Crossref
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Europe PMC
Received 2023-08-13
Accepted 2023-11-10
Published 2023-12-15

 

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