Ecotoxicological Studies of Cephalosporin Antibiotics on Daphnia Magna


  • Lovely Professional University, Department of Zoology, School of Bioengineering and Biosciences, Phagwara, Punjab, 144411, India


The present research was outlined to survey the intense and incessant poisonous quality of Cefixime and Cefotaxime antibiotics on Daphnia magna. The toxicity of Cefixime and Cefotaxime antibiotics was evaluated by 48h acute toxicity (US, EPA, 2002) and chronic toxicity (OECD guidelines 211 (OECD, 2012)). The data showed that EC50 of Cefixime was 78.78 mg/l and for Cefotaxime was 25.82 mg/l. Daphnia magna. showed more sensitivity to Cefotaxime, when compared with Cefixime antibiotic. Chronic toxicity showed that, Cefotaxime cause effects on reproduction but Cefixime had no adverse effect on Daphnia. The mortality rate enhanced and average number of neonates diminished as exposure to Cefotaxime antibiotic was increased. Daphnia. died (50%) at a concentration of 16.2 mg/l of Cefotaxime.


Cephalosporin, Non Target Organisms, Reproduction, Toxicity, Daphnia magna

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