Histopathological Findings in Uterus and Cervix of Hysterectomy Specimens


  • Ruby Hall Clinic, Department of Pathology, Pune, India
  • Dr. Vasantrao Pawar Medical College Hospital and Research Center, Department of Pathology, Nashik, 422003, India


Background: For centuries, the female reproductive system has been affected by various abnormalities and diseases and hence has been the subject of interest and the basis for the gynaecological practice. The uterus being a vital reproductive and hormone-responsive organ, is subjected to a variety of physiological changes and benign and malignant disorders. Aims and Objectives: To study the indications of hysterectomy, to study gross and histopathological features of uterus and cervix in hysterectomy specimens and correlate with clinical findings. Material and Methods: This was a descriptive study of the gross and histopathological findings of uterus and cervix in 150 hysterectomy specimens received in the department. The hysterectomy specimens received were fixed in 10% formalin for 24 hours, were examined grossly and necessary sections were obtained. The tissue pieces were then processed in automated tissue processor, well labelled paraffin blocks were made. Approximately 2-3μ thickness sections were cut with the help of microtome and were stained routinely by Hematoxylin & Eosin stain and special stains like PAS or other were used wherever necessary. The histopathological findings of uterus and cervix were noted and these findings were then correlated with clinical diagnosis. Results: Overall clinicopathological correlation was noted in all 150 cases. In cases of uterine fibroid it was 69.7% and 100% in case of endometrial carcinoma and cervical dysplasia. Most common pathology found was uterine leiomyomas in 48 cases and next to it was adenomyosis in 30 cases. Conclusion: It can be concluded that clinico-pathological correlation in case of endometrial cancer and uterine fibroid is excellent, but in case of DUB and prolapse uterus it varies. This signifies the importance of clinico-pathological correlation in all cases of hysterectomy to improve the clinical outcome and post-operative management.


Hysterectomy, Histopathology of Uterus and Cervix, Leiomyoma.

Subject Discipline

Obstetrics and Gynaecology

Full Text:


Qamar-Ur-Nisa, Habibullah, Shaikh TA, Hemlata, Memon F, Memon Z. Hystrectomies; An audit at a tertiary care hospital. Professional Med J. 2011 Mar; 18(1):46-50.

Watts WF, Kimbrough RA. Hysterectomy Analysis of 1000 consecutive operations. Obstet Gynecol. 1956 May; 7(5):483- 93.

Ajmera SK, Mettler L, Jonat W. Operative spectrum of hysterectomy in a German university hospital. J Obstet Gynecol India. 2006; 56(1):59-63.

Abdullah LS. Hysteretomy: A clinicopathologic correlation. Baharain Medical Bulletin. 2006 Jun; 8(2):1-6.

Gupta G, Kotasthane DS, Kotasthane VD. Hysterectomy: A Clinico-pathological Correlation of 500 cases. The Internet Journal of Gynaecology and Obstetrics 2010; 14(1).

Khan R, Sultana H. How does histopathology correlate with clinical and operative findings in abdominal hysterectomy?. JAFMC Bangladesh. 2010 Dec; 6(2):17-20.

Ranabhat SK, Shrestha R, Tiwari M, Sinha DP, Subedee LR. A retrospective histopathological study of hysterectomy with or without salpingo-ophorectomy specimens. JCMC. 2010; 1(1):26-9.

Bhide P, Bhide A. Uterine Adenomyosis. J Obstet Gynecol. 1994; 44(4):612-5.

Ramachandran T, Sinha P, Subramanium. Correlation between Clinico-pathological and Ultrasonographical Findings in Hysterectomy. JCDR. 2011 Aug; 5(4):737-40.

Tian J, Hu W. Cervical leiomyomas in pregnancy: report of 17 cases. Aust NZ J Obstet Gynaecol. 2012 Jun; 52(3):258-6.


  • There are currently no refbacks.