Study of Risk Factors and Clinical Profile of Stroke in Young Adults


Affiliations

  • MVPS Dr. Vasantrao Pawar Medical College Hospital and Research Center, Department of Medicine, Nashik, India

Abstract

Background: According to the Global Health Observatory, stroke is the second most common cause of death during last decade with a rising trend. Although stroke is considered to be the disease of older population, with the demographic shift the disease incidence is now shifting to younger age group. This shifting trend to younger age group pose a great concern to the world in terms of days lost to work and mortality. There is paucity of information on stroke in young individuals covering important types of stroke. Aims&Objectives: To study the clinical profile and risk factors associated with the stroke in young adults. Materials & Methods: The present descriptive study was carried out at tertiary care Hospital of Nasik from June 2011 to June 2013. A total of 40 consecutive cases between 15-45 years presenting with stroke were recruited for the study after taking prior informed consent. All cases underwent a detailed history taking, general and clinical examination along with all required Investigations. Data was analysed by SPSS software ver. 17 using appropriate statistical tests. Results: Ischemic stroke was the most common presentation and stroke prevalence was similar across both genders. Headache was the most common symptom followed by vomiting in all types of stroke patients. OC Pills and parity was found to significantly associated with CVST. Obesity, smoking and abnormal lipid profile was found to be significantly associated with thromboemblic stroke. Only 3 out of 40 stroke patients died during the course of study. Conclusion: OC Pills and parity were significantly associated with CVST while obesity, smoking and dyslipidemia were significantly associated with thromboemblic stroke. Outcome in young stroke patients was fairly good.

Keywords

Clinical Profile, Risk Factors, Stroke, Young Adults.

Subject Discipline

Neurology

Full Text:

References

Global Health Estimates Technical Paper WHO/HIS/ HSI/GHE/2013.3. WHO methods and data sources for global causes of death 2000‐2011. Availaible from: (http:// www.who.int/gho/mortality_burden_disease/causes_ death/2000_2011/en/index.html)

Powers AC. Harrison’s Principles of Internal medicine, 18th edition. Cerebrovascular Accident. Maryland, Baltimore: The McGraw-Hill Companies; 2012; 338:2275-304.

Das SK, Banerjee TK, Biswas A, et al. A prospective community- based study of stroke in Kolkata, India. Stroke. 2007; 38(3):906-10.

Dalal PM. Burden of Stroke: Indian perspective. Int J Stroke. 2006; 1:164-6.

Abraham J, Rao PSS, Imbraj SG, Shetty G. An epidemiological study of hemiplegia due to stroke in South India. Stroke. 1970; 1:477-81.

Aho K, Harmsen P, Hatano S. et al. Cerebrovascular disease in the community; results of a WHO collaborative study. Bulletin of World Health Organization. 1980; 58:113-30.

Munjal, Yash Pal, et al., editors. API textbook of medicine 18th edition. Cerebrovascular Accident. JP Medical Ltd; 2012. p. 758-65.

Kittner SJ, Giles WH, Macko RF, Hebel JR, Wozniak MA, Wityk RJ, et al. Homocyst(e)ine and risk of cerebral infarction in a biracial population: The stroke prevention in young women study. Stroke. 1999; 30:1554-60.

Bansal BC, Pralcash C, Jain AL, Brahmanandam KRV. C.V.D. in young individuals below the age of 40 years. Neurol (India). 1973; 21:11.

Chaturvedi M, Satoskar M, Khare MS, Kalgutkar AD. Sudden, unexpected and natural death in young adults of age between 18 and 35 years: A clinicopathological study. Indian J Pathol Microbiol. 2011; (54)1:47-50.

Dalal PM, Bhattacharjee M, Vairale J, Bhat P. Mumbai Stroke Registry (2005-2006) - Surveillance Using WHO Steps Stroke Instrument - Challenges and Opportunities. JAPI. 2008 Sep; 56:675-80.

Nayak SD, Nair M, Radhakrishnan K, Sarma PS. Ischaemic stroke in the young adult: clinical features, risk factors and outcome. Natl Med J India. 1997 May-Jun; 10(3):107-12.

Lipska K, Sylaja PN, Sarma PS, Thankappan KR, Kutty VR, Vasan RS, et al. Risk factors for acute ischaemic stroke in young adults in South India. J Neurol Neurosurg Psychiatry. 2007; 78:959-63.

Lidegard O, Soe M, Andersen NM. Cerebral thromboembolism among young women and men from Denmark 1977- 982. Stroke. 1986; 17:670-5.

Lisovoski F, Rousseaux P. Cerebral infarction in young people: A study of 148 patients of cerebral angiography. J Neurol Neurosurg Psychiatry. 1991; 54:576-7.

Adams HP Jr, Kappelle LJ, Biller J, Gordon DL, Love BB, Gomez F, Heffner M. Ischemic stroke in young adults. Experience in 329 patients enrolled in the Iowa Registry of stroke in young adults. Arch Neurol. 1995; 52:491-5.

Naess H, Nyland HI, Thomassen L, Aarseth J, Nyland G, Myhr KM. Incidence and short-term outcome of cerebral infarction in young adults in western Norway. Stroke. 2002; 33:2105-8.

Rasura M, Spalloni A, Ferrari M, De Castro S, Patella R, Lisi F, Beccia M. A case series of young stroke in Rome. Eur J Neurol. 2006; 13:146-52.

Rohr J, Kittner S, Feeser B, et al. Traditional risk factors and ischemic stroke in young adults: the Baltimore-Washington Cooperative Young Stroke Study. Arch Neurol. 1996; 53:603-7.

You RX, McNeil JJ, O'Malley HM, et al. Risk factors for stroke due to cerebral infarction in young adults. Stroke. 1997; 28:1913-8.

Bharucha NE, Bharucha EP, Bharucha AE, et al. Casecontrol study of completed ischemic stroke in the Parsis of Bombay: a population‐based study. Neurology. 1988; 38(3):490-2.


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