Anti-Dermatophytic Activity of Some Indian Medicinal Plants


Affiliations

  • Annamalai University, Department of Biochemistry, Annamalai Nagar, Tamilnadu, 608002, India
  • Annamalai University, Department of Microbiology, Rajah Muthiah Medical College and Hospital, Annamalai Nagar, Tamilnadu, 608002, India

Abstract

Objective: Anti-dermatophytic activities of 23 South Indian medicinal plant materials have been studied using five isolates of Trichophyton rubrum and four isolates of Trichophyton mentagrophytes obtained from the patients of Raja Muthiah Medical College & Hospital, India and compared. Materials and methods: Water and ethanol extracts were prepared and their minimum inhibitory concentration (MIC) and minimum fungicidal concentration (MFC) were determined. Results and conclusion: Ethanol extracts of plants exhibited more activity than water extracts. Among 23 plants garlic showed least MIC & MFC. In addition, ethanolic extracts of 11 plants showed less than 11.5 mg/ml MFC against T. rubrum and 9 plants showed less than 11.5 mg/ml MFC against T. mentagrophytes.

Keywords

Dermatophytosis, Trichophyton rubrum, Trichophyton mentagrophytes, Medicinal Plants.

Subject Discipline

Pharmacy and Pharmacology

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