Evaluation of Anti-Histaminic Activity of Beta vulgaris L. Root

Jump To References Section

Authors

  • ,IN
  • ,IN
  • ,IN
  • ,IN
  • ,IN

DOI:

https://doi.org/10.18311/jnr/2010/250

Keywords:

Beta vulgaris, Clonidine, Histamine, Clorpheniramine Maleate.
Therapeutic Drug Monitoring

Abstract

Clonidine, a a2 adrenoreceptor agonist induces dose dependent catalepsy in mice, which was inhibited by histamine H1 receptor antagonists but not by H2 receptor antagonist. Clonidine releases histamine from mast cells which is responsible for different asthmatic conditions. Roots of Beta vulgaris are sweet, expectorant and tonic, and are useful in psychopathy, cough, asthma and inflammation. In present investigation methanol extract of Beta vulgaris at doses 100 and 150 mg/kg, i.p. were evaluated for antihistaminic activity using clonidine induced catalepsy as catalepsy produced by clonidine is mediated by histamine via H1 receptors. Result of present investigation showed that both extract significantly (P<0.001) inhibit clonidine induced catalepsy. Phytochemical study found that presence of carbohydrate, glycosides, flavonoids and tannin.

Downloads

Download data is not yet available.

Metrics

Metrics Loading ...

Downloads

Published

2010-07-01

How to Cite

Taur, D. J., Nerkar, A. J., Bandal, R. S., Patil, R. N., & Patil, R. Y. (2010). Evaluation of Anti-Histaminic Activity of <I>Beta vulgaris</I> L. Root. Journal of Natural Remedies, 10(2), 105–108. https://doi.org/10.18311/jnr/2010/250

Issue

Section

Articles