Antibacterial and in vitro Anticancer Study of Methanol Extracts of Clitoria ternatea Leaves

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Authors

  • Arunava Das
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, Tamil Nadu ,IN
  • G. Shanmuga Priya
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, Tamil Nadu ,IN
  • S. Soundariya
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, Tamil Nadu ,IN
  • P. Deepesh
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, Tamil Nadu ,IN
  • Aileen Rose Edwin
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, Tamil Nadu ,IN
  • E. Vihashinee
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, Tamil Nadu ,IN
  • A. Rubiga
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, Tamil Nadu ,IN
  • S. Megavarthini
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, Tamil Nadu ,IN
  • R. Eswaran
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, Tamil Nadu ,IN
  • J. Bindhu
     Molecular Diagnostics & Biomolecule Characterization Lab, Department of Biotechnology, Bannari Amman Institute of Technology, Sathyamangalam – 638401, Erode, Tamil Nadu ,IN

DOI:

https://doi.org/10.18311/jnr/2020/24381

Keywords:

Antibacterial Activity, Anticancer Activity, Clitoria ternatea, GC-MS Analysis, Phytochemical Screening, MTT Assay

Abstract

Clitoria ternatea is often known as butterfly pea plant by the natives and is one of the major plants used in Ayurveda and traditional medicine worldwide. It is also used in food and cosmetic industries for various purposes. In this study, methanol leaf extract of Clitoria ternatea was studied for its antibacterial and in vitro anticancer study against human promyelocytic leukemia cells (HL60). Secondary metabolites like alkaloids, phlobatannin, triterpenoids, flavonoids, lipids, steroids, terpenoids, tannins and glycosides are identified in the extract by phytochemical screening. Leaf extract showed the presence of ethers and carboxylic acid groups (GCMS analysis). The leaf extract showed resistance against Salmonella typhi. Thus, from this study it can be concluded Clitoria ternatea leaves methanol extract has bioactive compounds showing anticancer activity against HL60 cells.

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Published

2020-06-11

How to Cite

Das, A., Shanmuga Priya, G., Soundariya, S., Deepesh, P., Rose Edwin, A., Vihashinee, E., Rubiga, A., Megavarthini, S., Eswaran, R., & Bindhu, J. (2020). Antibacterial and <i>in vitro</i> Anticancer Study of Methanol Extracts of <i>Clitoria ternatea</i> Leaves. Journal of Natural Remedies, 20(2), 96–102. https://doi.org/10.18311/jnr/2020/24381

Issue

Volume 20, Issue 2, April 2020

Section

Research Articles
Crossref
Scopus
Google Scholar
Europe PMC
Received 2019-10-29
Accepted 2020-02-19
Published 2020-06-11

 

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