Wound Healing Profile of Sauropus androgynus in Wistar Rats

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  • ,IN
  • ,IN
  • ,IN

DOI:

https://doi.org/10.18311/jnr/2009/235

Keywords:

Sauropus Androgynus, Wound Healing, Wound Re-Epithelization, Wound Contraction.
Therapeutic Drug Monitoring

Abstract

Objective: To evaluate the effect of Sauropus androgynus on wound healing. Materials and Methods: Excision and incision wound models were used to evaluate the wound-healing activity of 5% Sauropus androgynus on Wistar rats of either sex. Results: Sauropus androgynus extract promoted the wound healing activity significantly in both wound models studied, while no action was seen with ointment base. It augmented wound contraction significantly (P<0.001), re-epithelization very significantly (P<0.0001) and increase in wound breaking strength (P<0.001). Histological evaluation of wound tissue showed abundant collegenation, fibroblast and lesser macrophages in animal treated with 5% Sauropus androgynus when compared to control and ointment base. Conclusion: Extract of Sauropus androgynus promotes wound-healing activity.

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Published

2009-06-01

How to Cite

Bhaskar, A., Ramesh, K. V., & Rajeshwari, S. (2009). Wound Healing Profile of <I>Sauropus androgynus</I> in Wistar Rats. Journal of Natural Remedies, 9(2), 159–164. https://doi.org/10.18311/jnr/2009/235

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