Impact of Supplementation of Carotino Oil on Blood Glucose, Lipid Profile and Antioxidant Status of Healthy Volunteers


Affiliations

  • Avinashilingam Institute for Home Science and Higher Education for Women, Department of Food Science and Nutrition, Coimbatore, 641 043, India

Abstract

The study aimed at assessing the impact of supplementation of nutraceutical rich carotino oil on the blood glucose, lipid profile and antioxidant status of healthy volunteers. Among the 40 subjects selected at random based on their willingness to participate in the study, 20 formed the control group while the other 20 formed the experimental group. Purposive sampling was used for the selection of subjects. Fifteen mL of carotino oil was given to a group of 20 healthy subjects each in the experimental group I (20-40 years) and 10 subjects in experimental group II (40-60 years), respectively whereas the 10 subjects each in the control groups I and II belonging to the respective age categories were not given any supplementation. Before and after supplementation, the biochemical parameters namely fasting blood glucose, lipid profile including total cholesterol, low density lipoprotein and high density lipoprotein and antioxidant status of the subjects namely a carotene, vitamin C, superoxide dismutase and total antioxidant activity were analysed. The study in healthy volunteers showed that carotino oil helped to maintain the blood glucose level, improved antioxidant status and lipid profile. Hence, carotino can be recommended for degenerative disorders namely, type II diabetes mellitus and cardiovascular diseases.

Keywords

Carotino Oil, Blood Glucose, Lipid Profile, Antioxidant Status.

Subject Discipline

Pharmacy and Pharmacology

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References

Processed Food Industry, 2009, 43, 64.

http://www.carotino.co.uk./carotino.asp

Ramya Siva Selvi, M., Kowsalya, S., Ramalingam, S. and Ramnathan, M., Nutraceutical potentials of carotino oil and its effect on blood glucose and antioxidant enzymes in streptozotocin induces diabetic rats., J. Agri. Sci. Technol, Al, 2011, 1, 1079-1088.

Kothari, C.R., Research Methodology, New age International public limited, New Delhi. 2002, 56.

Indian Council of Medical Research (ICMR), Nutritive Value of Indian Foods', National Institute of Nutrition, Hyderabad, 2012, 74-78.

Bhaskarachary, K., Sudershan Rao, V. and Subba Rao, G.M., A hand book on concepts and skills for practical dietetics, Indian Dietetic Association, AP Chapter, Hyderabad. 2010, 13.

Srilakshmi, B., Dietetics, New Age International Publishing Ltd 5th edition, 2006, 306. 3479s-3485s.

Kaser and Stekol. Determination of carotenes in serum using the carr - price reaction method. Practical clinical biochemistry, 1943, 217.

Roe, J.H. and Kuether, C.A., Detection of ascorbic acid in whole blood and urine through the 2,4 DNPH derivative of dehydroascorbic acid. J. Biochem., 1943, 147, 399-407.

Marklund and Marklund. A study of oxidative stress in paucibacillary and multibacillary leprosy. Health Publications, 1974, 1-3.

Koracevic, D., Koracevic, G., Djordjevic, V., Andrejevic, V. and Cosic. Method for the measurement of antioxidant activity in human fluids. J. Clin. Pathol, 2001, 356-361.

ICMR, 41st National conference workshop on assessment of nutritional status and dissemination of new RDA for Indians, ICMR, Hyderabad, 2009, 3.

Bamji, M., Pralhad, R. and Reddy, V., The text book of human nutrition, Oxford and IBH Publishing Co, Pvt, Ltd II edition, 2004, 365-366.

American Diabetes Association (ADA), Standards of Medical Care in Diabetes Position Statement of the American Diabetes Association, 2004, 27, S84-S87.

Ros, E., Dietary cis - monounsatured fatty acids and metabolic control in type II diabetes. Am. J. Clin. Nutri., 2003, 78, 617S-625S.

Ghafoorunissa. Palm oil Indian diets. Nutritional and health implications. Nutrition News 1995, 3, 26-28.

Oguntibeju, O., Esterhuyse, A.J. and Truter, E.J., Possible role of red palm oil supplementation in reducing oxidative stress in HIV/AIDS and TB patients: A Review. J. Med. PL Res., 2009, 4, 188-196.

Truswell, Choudhury, N. and Roberts, D.C.K., Double - blind comparison of plasma lipid in healthy subjects eating potato chips fried in palm olein or canola oil. Nutr. Res. 1992, 12, S34-S52.

Zhang, J., Ping, W., Chunrong, W., Shou, X.C. and Keyou, G., Non hypercholesterolemic effect of a palm oil diet in Chinese adults. J. Nutr., 1997, 127, 509S-513S.

Nader. Free radical scavenging activity of curcuminoids. Drug Res. 1996, 46, 169-171.

Kannen. New Dietary oil for the new millennium. Red palm oil, Total Health, 2000, 22, 62-63.

Rukmini, C, Red palm oil to combat vitamin deficiency in developing countries. Fd. Nutr. Bull., 1994, 15, 126-129.

Rex, Gregory, J., Foster, K., Tyler, H. and Wiseman, M., The Dietary and Nutritional survey of British adults. London: H.M. Stationary office, 1990, 25.

Jyothi, P., A study of oxidative stress in paucibacillary and multibacillary leprosy, Ind. J. Dermatol. Venereol. Leprol., 2008, 46, 853-55.

Moussa, S.A., Oxidative stress in diabetes mellitus. Romanian J. Biophys., 2008, 18, 225-236.

Rumley, A.G. and Paterson, J.R., Analytical aspects of antioxidants and free radical activity in clinical biochemistry. Ann. Clin. Biochem., 1998, 35, 181-200.


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