Pulmonary Sarcomatoid Carcinoma


Affiliations

  • Government Medical College, Jammu, Jammu City, Jammu and Kashmir, 180001, India

Abstract

Pulmonary Sarcomatoid Carcinoma (PSC) is a poorly differentiated NSCLC with sarcoma like differentiation (spindle/giant cell) or a component of sarcoma (malignant bone/cartilage/skeletal muscle). WHO grading 2015, classifies sarcomatoid ca into five histological types: pleomorphic carcinoma, spindle cell carcinoma, giant cell carcinoma, carcinosarcoma and pulmonary blastoma.

Keywords

Elderly, Lung, Malignancy, Prognosis

Subject Discipline

Pulmonology

Full Text:

References

WHO Classification of Tumours of the Lung, Pleura, Thymus and Heart. Lyon: International Agency for Research on Cancer; 2015.

Koss MN, Hochholzer L, Frommelt RA. Carcinosarcomas of the lung: A clinicopathologic study of 66 patients. Am J Surg Pathol. 1999; 23(12):1514–26. https://doi.org/10.1097/00000478-199912000-00009 PMid:10584705

Litzky LA. Pulmonary sarcomatous tumors. Arch Pathol Lab Med. 2008; 132(7):1104–17. PMid:18605765

Nakajima M, Kasai T, Hashimoto H, Iwata Y, Manabe H. Sarcomatoid carcinoma of the lung: A clinicopathologic study of 37 cases. Cancer. 1999; 86(4):608–16. https://doi.org/10.1002/(SICI)1097-0142(19990815)86:4<608::AIDCNCR9> 3.0.CO;2-1

Franks TJ, Galvin JR. Sarcomatoid carcinoma of the lung: Histologic criteria and common lesions in the differential diagnosis. Arch Pathol Lab Med. 2010 Jan; 134(1):49–54. PMid:20073605

DH D, SP H. Cancer Sci. 1987; 98:1914–1920.

Italiano A, Cortot AB, Ilie M, et al. EGFR and KRAS status of primary sarcomatoid carcinomas of the lung: Implications for anti-EGFR treatment of a rare lung malignancy. Int J Cancer. 2009; 125:2479–82. https://doi.org/10.1002/ ijc.24610 PMid:19681124

Fishback NF, Travis WD, Moran CA, Guinee DG, Jr, McCarthy WF, Koss MN. Pleomorphic (spindle/giant cell) carcinoma of the lung. A clinicopathologic correlation of 78 cases. Cancer. 1994; 73:2936–45. https://doi.org/10.1002/1097-0142(19940615)73:12<2936::AIDCNCR2820731210> 3.0.CO;2-U

Rossi G, Cavazza A, Sturm N, et al. Pulmonary carcinomas with pleomorphic, sarcomatoid, or sarcomatous elements: A clinicopathologic and immunohistochemical study of 75 cases. Am J Surg Pathol. 2003; 27(3):311–24. https://doi.org/10.1097/00000478-200303000-00004 PMid:12604887


Refbacks

  • There are currently no refbacks.