Assessment of Rapid Dipstick Test for Diagnosis of Urinary Tract Infection in Asymptomatic Pregnant Female


Affiliations

  • Sri Guru Ram Das Institute of Medical Sciences and Research, Amritsar, Punjab, India

Abstract

Background:Bacteriuria during pregnancy has been known to cause many complications like low birth weight and premature delivery.

Objective: This study was done to evaluate the diagnostic accuracy of rapid dipstick test to predict urinary tract infection in pregnancy against the gold standard urine culture.

Material&Methods: A total of 200 mid stream urine samples were collected from asymptomatic pregnant females. These specimens were cultured in blood agar and MacConkey's agar by using the standard loop technique and incubated aerobically at 37°C overnight. The criterion for clinically significant bacteriuria was either a pure or predominant culture of >105 colony forming units (CFU)/ml. All the specimens were also examined microscopically for pyuria and bacteriuria.

Results: The prevalence of asymptomatic bacteriuria in pregnancy was 15 % in our study. The sensitivity and the specificity for leucocyte esterase were 85.7% and 74.4% and for nitrites, they were 64.2% and 72%.

Conclusion: The study revealed that use of either leukocyte esterase or nitrite for screening of asymptomatic bacteriuria in pregnancy was associated with many false positive and negative results when compared with the gold standard urine culture method. By using their combination maximum negative predictive value of .98 was achieved.


Keywords

Dipstick Test, Asymptomatic Bacteriuria, Urinary Tract Infection, Pregnancy, Urine.

Subject Discipline

Urology and Nephrology

Full Text:

References

RJ Girish babu, R Srikrishna, ST Ramesh. Asymptomatic bacteriuria in pregnancy. Int J Bio Med Res 2011;2(3):740-2.

Jayalakshmi J, Jayaram VS. Evaluation of various screening tests to detect asymptomatic bacteriuria in pregnant women. Indian J Pathol Microbiol 2008;51(3):379-381.

Gayathree L, Shetty S, Deshpande SR, Venkatesh DT. Screening for asymptomatic bacteriuria in pregnancy: An evaluation of various screening tests in Hassan District Hospital, India. JCDR 2010;4(4):2702-6.

Balamurgan S, Chaitanya S, Jayapriya S, Priyadarshini S, Jeya M, Ramesh RK. Reagent strip testing(RST) for asymptomatic bacteriuria in pregnant women. A cost effective screening tool in under resourced settings. JCDR 2012;6(4):671-3.

Enayat K, Fariba F, Bahram N. Asymptomatic bacteriuria among pregnant women referred to outpatient clinics in Sanandaj, Iran. Int Braz J Urol 2008;34(6):699-707.

Imade PE, Izekor PE, Eghafona NO, Enabulele OI, Ophori E. Asymptomatic bacteriuria among pregnant women. North Am J Med Sci 2010;2(6):263-266.

Abdullah AA, Al-Moslih MI. Prevalence of asymptomatic bacteriuria in pregnant women in Sharjah, United Arab Emirates. Eastern Mediterranean Health Journal 2005;11(5):1045-1052.

Khattak AM, Khattak S, Khan H, Ashiq B, Mohammad D, Rafiq M. Prevalence of asymptomatic bacteriuria in pregnant women. Pak J Med Sci 2006;22(2):162-166.

Fiona Smaill. Asymptomatic bacteriuria in pregnancy. Best Practice and Research Clinical Obstetrics and Gynaecology 2007;21(3):439-450.

Patel HD, Livsey SA, Swann RA, Bukhari SS. Can urine dipstick testing for urinary tract infection at the point of care reduce the laboratory workload? J Clin Pathol 2005;951–54.

Tincello D, Richmond D. Evaluation of reagent strips in detecting asymptomatic bacteriuria in early pregnancy: prospective case series. Br Med J 1998;316(7):435-437.

Bachman JW, Heise RH, Naessens JM and Timmerman MG. A study of various tests to detect asymptomatic urinary tract infections in an obstetric population. JAMA 1993;270:1971-4.

Robertson A, Duff P. The nitrite and leukocyte esterase tests for the evaluation of asymptomatic bacteriuria in obstetric patients. Obstet Gynecol1988;71(6):878-881.


Refbacks

  • There are currently no refbacks.