Histological Patterns of Ovarian Neoplasms – A Five Year Experience in North-East India
Background: Ovary is one of the common sites of neoplasm in females. They manifest in wide spectrum of clinical, morphological and histological features. Ovary is the second most common site of primary malignancy in female genital tract.
Objectives: To study the frequency of different histological types of ovarian tumors and to analyze age distribution of these tumors.
Materials and Methods: This was a retrospective study of all cases of ovarian tumors received at Pathology Department of Agartala Government Medical College during the period of 5 years from January 2012 to December 2016.
Results: A total number of 242 cases were studied. Among these 189 cases (78.1%) were benign, 12 cases (4.96%) were borderline and 41 cases (16.94%) were malignant. Benign neoplasms were most commonly seen between 3rd and 5th decade of age whereas malignant neoplasms after 4th decade. Serous cystadenoma was the commonest benign tumor followed by mucinous cystadenoma and mature cystic teratoma. Among the malignant surface epithelial tumors, mucinous cystadenocarcinoma was most common, followed by serous cystadenocarcinoma.
Conclusion: Benign ovarian neoplasms outnumber the malignant ones in all age groups. Surface epithelial tumors are the most common class of tumors and mucinous cystadenocarcinoma is the commonest malignant neoplasm.
Mondal S, Banyopadhya R, Nag D, Roychowdhury S, Mondap P, Sinha S. Histological pattern, bilaterality and clinical evaluation of 957 ovarian neoplasms: A 10 – year study in a tertiary hospital of eastern India. Journal of Cancer research and Therapeutics 2011;7(4):433-7.
Sen V, Sankaranaryana R, Mandal S, Romana AV, Parkin DM, Siddique M. Cancer patterns in Eastern India. The first report of Kolkata Cancer registry. Int J Cancer 2002;100:86-91.
Tortolerol, Mitchel FM, Rhodes HE. Epidemiology and screening of ovarian cancer. Obstet Gynaecol Clin North Am 1994;21:63-75.
Scully Robert E, Young Robert H. Clement Phillip B. Atlas of tumor pathology. Tumors of ovary, maldeveloped gonads, fallopian tube and broad ligament. 3rd series, fascicle 23. Armed force institute of pathology, 1999.
Shahrzad Ehdaivand. WHO classification of ovarian neoplasm. Pathology outline.com website http:/www.pathologyoutlinescom/topic/ovar ytumorwhoclassif.html.Accessed February 27th.2017
Murthy NS, Shalini S, Suman G, Pruthvish S, Mathew A. Changing trends in incidence of ovarian cancer- the Indian scenario. Asian Pac J Cancer Prev 2009;10:1025-30.
Yancik R. Ovarian cancer. Age contrast in incidence, histology, disease stage at diagnosis, and mortality. Cancer 1993;71(S2):517-23.
Quirk JT, Natarajan N. Ovarian cancer incidence in United States, 1992-99. Gynecol Oncol 2005;97:519-23.
Pilli GS, Suneeta KP, Dhaded AV, Yenni VV. Ovarian tumor. A study of 282 cases. J Indian Med Assoc 2002;100:420-7.
Ahmad Z, Kayani N, Husan SH, Muzaffar S, Gill MS. Histological pattern of ovarian neoplasm. Pak J Pathol 2005;16:28-32.
M Yogambal, P Arunalatha, K Chandramouleeswari, V Palaniappan. Ovarian tumors – Incidence and distribution in tertiary referral center in south India. IOSR-JDMS 2014;13(2):74-80.
Nirali N Thakkar, Shaila N Shah. Histopathological Study of Ovarian Lesion. International journal of Science and Research (IJSR) 2015;4(10)1745-9.
Dimpal Modi, Gunvanti B Rathod, KN Delwadia, HM Goswami. Histopathological pattern of neoplastic ovarian lesions. IAIM 2016;3(1):51-7.
R Jha, S Karki. Histopathological pattern of Ovarian tumors and their age distribution. Nepal Med coll J 2008;10(2):81-5.
Swati Singh, Veena Saxena, Suman Lata Khatri, Sumit Gupta, Jayadeep Garewal, Krishna Dubey. Histopathological Evaluation of Ovarian Tumors. Imperial Journal of Interdisciplinary Research (IJIR), 2016;2(4):435-9.
Seidman JD, Harkaynae SI, Cosin JA, Ryu HS, Haiba M, Boice CR. Testing of two binary grading system for FIGO stage III serous carcinoma of the ovary and peritoneum. Gynecol Oncol 2006;103:703-8.
Choudhury S, Hussain R. Squamous cell carcinoma arising in mature cystic teratoma (dermoid cyst)—a rare presentation. J Pak Med Assoc 2013;63(4):521-3.
Barkat RR. Borderline tumors of Ovary. Obstet Gynaecol Clin North Am 1994;21:93-105.
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