Synthesis, Characterization and Anthelmintic Activity of Novel 3-Benzyl-2-(4'-Substituted Phenyl)-4(5H)-(4''-Nitrophenyl Amino)-1, 3-Oxazolidines Derivatives


Affiliations

  • D.C.R.M. Pharmacy College, Department of Pharmaceutical Chemistry, Inkollu, Andhra Pradesh, 523167, India
  • IIT Madras, Department of Biotechnology, Chennai, Tamil Nadu, 600036, India
  • VIT University, School of BioScience and Technology, Vellore, Tamil Nadu, 632014, India

Abstract

The study aimed at screening synthetic compounds for pharmacological activity. The anthelmintic activity of 3 - benzyl - 2 - (4' - substituted phenyl) - 4(5 H ) - (4'' - nitrophenyl amino) - 1, 3 - oxazolidines 6a - e compounds was evaluated by Passive avoidance test . The purity of the synthesized compounds was characterized by means of IR, 1 H - NMR, mass spectral and elemental analysis.

Keywords

Oxazolidine, Anthelmintic Activity.

Subject Discipline

Pharmacy and Pharmacology

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