Pharmacognostic Standardization, Phenolic and in Vitro Antioxidant Activity of Silene villosa (Family: Caryophyllaceae)


Affiliations

  • College of Pharmacy, Prince Sattam bin Abdulaziz University, Department of Pharmacognosy, Al-Kharj, 11942, Saudi Arabia

Abstract

The present study was designed to explore some of the quality principles and in vitro antioxidant exploration of Silene villosa “a non-intentional” herb. The pharmacognostical study and phytochemical evaluation of the herbs of S. villosa was carried out following the reported methods. The total phenolic contents and antioxidant potential of the methanol extract was also evaluated applying the standard methods. Microscopic features of the Transverse Section (T.S) of the root were observed as epidermis, medullary rays, xylem cells, phloem cells. The microscopic study of the powder showed the presence of spiral vessels, lignified fibre or tannin containing cells. The extractive value showed the water soluble materials were higher than the alcohol soluble materials. Primarily phytochemical analysis and total phenolic contents (11.78±0.169 %) in powder and extract respectively were conducted. The methanol extract of S. villosa showed dose dependent antioxidant activity. The present study helps in authentication of S. villosa and enhances further exploration of the health benefits due to the presence of phenolic contents and antioxidant property.

Keywords

Antioxidants, Pharmacognostical, Phytochemicals, Silene villosa, Total Phenols

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